gene 507 words KG: CAMKK2
Contents

CAMKK2 Gene

🧬 Gene Info
Gene SymbolCAMKK2
Full NameCalcium/Calmodulin-Dependent Protein Kinase Kinase 2
Chromosome12q24.13
Protein TypeKinase
FunctionCAMKK2 is a serine/threonine protein kinase
Molecular Weight65 kDa
PathwaysAMPK, AMPK Signaling, ampk, mTOR
UniProt IDQ96HS5
NCBI Gene ID8146
Ensembl IDENSG00000110939
OMIM615092
GeneCardsCAMKK2
Human Protein AtlasCAMKK2
AMPK activationPrimary upstream kinase for AMPKα
CaMK1 activationActivates CaMK1 for nuclear signaling
Associated DiseasesAging, Alzheimer, dementia, Diabetes, Ferroptosis
InteractionsACETYL-COA, AIF1, AMPK, ARC, ATP, AUTOPHAGY
KG Connections80 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Blood-Brain Barrier SPM Shuttle System
Score: 0.53
Piezoelectric Nanochannel BBB Disruption
Score: 0.52

Related Analyses (4)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

ATP P2X3 Receptor Neurons
cell · KG edge: inhibits
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: inhibits
ARHGEF2 Gene
gene · KG edge: interacts_with
ARNTL Gene — Aryl Hydrocarbon Receptor Nuclear Transloc
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GAIN expressed_in CAMKK2
CAMKK2 expressed_in P2RX7
CAMKK2 expressed_in P2RX4
TFEB inhibits CAMKK2
CAMKK2 inhibits LC3
STAT3 associated_with CAMKK2
KDM5A associated_with CAMKK2
TYRO3 associated_with CAMKK2
SREBF1 associated_with CAMKK2
CAMKK2 associated_with CDKN1A

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