gene 2,330 words KG: ATP6V0D1
Contents

ATP6V0D1 — ATPase H+ Transporting V0 Subunit D1

🧬 Gene Info
Gene SymbolATP6V0D1
Full NameATPase H+ Transporting V0 Subunit D1
Chromosome16p13.3
Protein TypeV-ATPase subunit (V0 domain)
Functionencodes a critical subunit of the vacuolar-type H+-ATPase (V-ATPase), a multisubunit proton pump essential for acidification of intracellular compartments throughout the cell.
Primary ExpressionBrain, Liver, Kidney, Ubiquitous
Gene TypeProtein coding
PathwaysAutophagy, Inflammasome
UniProt IDP61421
NCBI Gene ID9114
Ensembl IDENSG00000159720
OMIM618171
GeneCardsATP6V0D1
Human Protein AtlasATP6V0D1
Associated DiseasesMelanoma, Tumor
InteractionsACTB, ATG14, ATG16L1, AUTOPHAGY, INFLAMMATION, LYSOSOME
KG Connections34 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71
LRP1-Dependent Tau Uptake Disruption
Score: 0.60
APOE-Dependent Autophagy Restoration
Score: 0.88
Autophagosome Maturation Checkpoint Control
Score: 0.71
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Extracellular Vesicle Biogenesis Modulation
Score: 0.58

Related Analyses (2)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Validate Mitochondria-Lysosome Contact Site Dysfunction in P
validation · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40

See Also (15)

CASP1 Gene
gene · KG edge: associated_with
AIM2 Inflammasome Modulation Therapy for Neurodegenerat
idea · KG edge: associated_with
ACTB Gene
gene · KG edge: activates
ATG16L1 - Autophagy Related 16 Like 1
gene · KG edge: activates
Lysosomal Associated Membrane Protein 1 (LAMP1)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ASC associated_with ATP6V0D1
AIM2 associated_with ATP6V0D1
SQSTM1 associated_with ATP6V0D1
VAMP8 associated_with ATP6V0D1
ULK1 associated_with ATP6V0D1
CTSB associated_with ATP6V0D1
ATP6V0D1 associated_with NLRP3
ATP6V0D1 activates ACTB
ATP6V0D1 associated_with IL6
ATP6V0D1 associated_with LC3

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.