protein 519 words KG: AIM2
Contents

AIM2 Protein

🔬 Protein Info
Gene SymbolAIM2
Protein FamilyAIM2-like receptor (ALR)
FunctionAIM2 functions as a cytosolic DNA sensor forming the AIM2 inflammasome.
Subcellular LocalizationCytoplasm
Molecular Weight39 kDa
Amino Acids200 aa
PathwaysApoptosis, Autophagy, Cholesterol, Ferroptosis, Immune Response
UniProt IDQ9WZE6
GeneCardsAIM2
Human Protein AtlasAIM2
Associated DiseasesAls, Atherosclerosis, Cancer, Dementia, Infection
InteractionsACTB, Actin, ALZHEIMER, AMPK, AND, APOPTOSIS
KG Connections403 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (6)

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Score: 0.53

Related Analyses (9)

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See Also (7)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: inhibits
Apoptosis in Neurodegeneration
entity · KG edge: activates
ACTB Gene
gene · KG edge: activates
ASC (PYCARD)
gene · KG edge: activates
ATG14 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

IL1B associated_with AIM2
CASP1 associated_with AIM2
ATG5 associated_with AIM2
NLRC4 associated_with AIM2
ASC associated_with AIM2
NLRP3 associated_with AIM2
AIM2 associated_with TNF
AIM2 associated_with MARCH7
AIM2 associated_with PYCARD
AIM2 associated_with LAMP1

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