Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FRONTAL LOBE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FRONTAL LOBE |
graph TD
FRONTAL_LOBE["FRONTAL LOBE"]
DEMENTIA["DEMENTIA"] -->|"expressed in"| FRONTAL_LOBE
GRN["GRN"] -->|"expressed in"| FRONTAL_LOBE
MAPT["MAPT"] -->|"expressed in"| FRONTAL_LOBE
C9ORF72["C9ORF72"] -->|"expressed in"| FRONTAL_LOBE
MITOCHONDRIA["MITOCHONDRIA"] -->|"expressed in"| FRONTAL_LOBE
ALZHEIMER["ALZHEIMER"] -->|"expressed in"| FRONTAL_LOBE
RAS["RAS"] -->|"expressed in"| FRONTAL_LOBE
MTOR["MTOR"] -->|"expressed in"| FRONTAL_LOBE| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Frontotemporal Dementia | expressed_in | disease | 0.85 |
| frontotemporal dementia | affects | disease | 0.60 |
| autism | affects | disease | 0.60 |
| neurodegeneration | affects | disease | 0.60 |
| Frontotemporal Dementia | associated_with | disease | 0.55 |
| Dementia | associated_with | disease | 0.55 |
| DEMENTIA | expressed_in | gene | 0.55 |
| Neurodegeneration | associated_with | disease | 0.55 |
| Aging | associated_with | disease | 0.55 |
| Als | associated_with | disease | 0.55 |
| Traumatic Brain Injury | associated_with | disease | 0.55 |
| ALZHEIMER | expressed_in | gene | 0.55 |
| Alzheimer | associated_with | disease | 0.55 |
| RAS | expressed_in | gene | 0.55 |
| EPILEPSY | expressed_in | gene | 0.55 |
| Epilepsy | associated_with | disease | 0.55 |
| MITOCHONDRIA | expressed_in | gene | 0.55 |
| LDHB | expressed_in | gene | 0.55 |
| RHEB | expressed_in | gene | 0.55 |
| C9ORF72 | expressed_in | gene | 0.55 |
| MTOR | expressed_in | gene | 0.55 |
| MAPT | expressed_in | gene | 0.55 |
| CAMK2A | expressed_in | gene | 0.55 |
| GRN | expressed_in | gene | 0.55 |
| NDUFS6 | expressed_in | gene | 0.55 |
| GAP43 | expressed_in | gene | 0.55 |
| HSPE1 | expressed_in | gene | 0.55 |
| STMN1 | expressed_in | gene | 0.55 |
| SNCB | expressed_in | gene | 0.55 |
| SNCG | expressed_in | gene | 0.55 |
| Neural Progenitor | expressed_in | cell_type | 0.50 |
| Neuron | expressed_in | cell_type | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FRONTAL LOBE in their description or question text
No additional research found