protein

SNCG

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNCG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections

0Hypotheses

0Analyses

14Outgoing

10Incoming

0Experiments

0Debates

Summary

Comprehensive page for Gamma-Synuclein (SNCG) in Neurodegeneration and Cancer

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🔬 Protein Info

Gene Symbol	SNCG
Full Name	Gamma-Synuclein
Chromosome	10q23.2-q23.3
Protein Family	Synuclein (alpha, beta, gamma)
Function	encodes gamma-synuclein (also known as synoretin or BCSG1), the third member of the synuclein family of proteins
Primary Expression	the nervous system and has been implicated in various neurodegenerative processes
Molecular Weight	13.0 kDa
Amino Acids	127 aa
UniProt ID	P37841
NCBI Gene ID	6623
Ensembl ID	ENSG00000173267
OMIM	162267
GeneCards	SNCG
Human Protein Atlas	SNCG
Alpha-synuclein (SNCA)	The most studied member, central to Parkinson's disease pathogenesis
Associated Diseases	neurodegeneration
KG Connections	24 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SNCG — AlphaFold P37841 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

SNCG Gene — Gamma-Synuclein

gene · 1656 words

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SNCG Protein (Gamma-Synuclein)

protein · 1777 words

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Pathway Diagram

graph TD
    SNCG["SNCG"]
    Traumatic_Brain_Injury{"Traumatic Brain Injury"}
    SNCG -->|"expressed_in"| Traumatic_Brain_Injury
    STMN1(["STMN1"])
    SNCG -->|"expressed_in"| STMN1
    GAP43(["GAP43"])
    SNCG -->|"expressed_in"| GAP43
    HSPE1(["HSPE1"])
    SNCG -->|"expressed_in"| HSPE1
    BRAIN_INJURY(["BRAIN INJURY"])
    SNCG -->|"expressed_in"| BRAIN_INJURY
    MAPT(["MAPT"])
    SNCG -->|"expressed_in"| MAPT
    NDUFS6(["NDUFS6"])
    NDUFS6 -->|"expressed_in"| SNCG
    LDHB(["LDHB"])
    LDHB -->|"expressed_in"| SNCG
    SNCB(["SNCB"])
    SNCB -->|"expressed_in"| SNCG
    style SNCG fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7

Outgoing (14)

Target	Relation	Type	Str
Traumatic Brain Injury	expressed_in	disease	0.65
NDUFS6	expressed_in	gene	0.60
BRAIN INJURY	expressed_in	gene	0.60
LDHB	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
MAPT	expressed_in	gene	0.60
STMN1	expressed_in	gene	0.60
GAP43	expressed_in	gene	0.60
HSPE1	expressed_in	gene	0.60
Frontal Lobe	expressed_in	brain_region	0.55
Temporal Lobe	expressed_in	brain_region	0.55
Cortex	expressed_in	brain_region	0.55
Proteins	expressed_in	protein	0.50
STMN1	co_expressed_with	gene	0.50

Incoming (10)

Source	Relation	Type	Str
LDHB	expressed_in	gene	0.60
HSPE1	expressed_in	gene	0.60
STMN1	expressed_in	gene	0.60
GENES	expressed_in	gene	0.60
NDUFS6	expressed_in	gene	0.60
MAPT	expressed_in	gene	0.60
SNCB	expressed_in	gene	0.60
NDUFS6	co_expressed_with	gene	0.50
SNCB	co_expressed_with	gene	0.50
GAP43	expressed_in	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SNCG in their description or question text

No additional research found