Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DS-DB4A006EA647: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | DS-DB4A006EA647 |
graph TD
DS_DB4A006EA647[DS-DB4A006EA647]
DS_DB4A006EA647 -->|data_in| ABCA7[ABCA7]
DS_DB4A006EA647 -->|data_in| AP2A1[AP2A1]
DS_DB4A006EA647 -->|data_in| APOE[APOE]
DS_DB4A006EA647 -->|data_in| ATAD3A[ATAD3A]
DS_DB4A006EA647 -->|data_in| Antigen_processing_and_present[Antigen processing and presentation]
DS_DB4A006EA647 -->|data_in| Apoptosis[Apoptosis]
DS_DB4A006EA647 -->|data_in| BCL2L11[BCL2L11]
DS_DB4A006EA647 -->|data_in| BIN1[BIN1]
DS_DB4A006EA647 -->|data_in| CAMK4[CAMK4]
DS_DB4A006EA647 -->|data_in| CASP3[CASP3]
ABCA7 -->|provides_data_for| DS_DB4A006EA647
AP2A1 -->|provides_data_for| DS_DB4A006EA647
APOE -->|provides_data_for| DS_DB4A006EA647
ATAD3A -->|provides_data_for| DS_DB4A006EA647
Antigen_processing_and_present -->|provides_data_for| DS_DB4A006EA647
Apoptosis -->|provides_data_for| DS_DB4A006EA647
BCL2L11 -->|provides_data_for| DS_DB4A006EA647
BIN1 -->|provides_data_for| DS_DB4A006EA647
CAMK4 -->|provides_data_for| DS_DB4A006EA647
CASP3 -->|provides_data_for| DS_DB4A006EA647| Target | Relation | Type | Str |
|---|---|---|---|
| Endocytosis | data_in | pathway | 1.00 |
| ABCA7 | data_in | entity | 1.00 |
| AP2A1 | data_in | entity | 1.00 |
| APOE | data_in | entity | 1.00 |
| ATAD3A | data_in | entity | 1.00 |
| Antigen processing and presentation | data_in | entity | 1.00 |
| BCL2L11 | data_in | entity | 1.00 |
| BIN1 | data_in | entity | 1.00 |
| CAMK4 | data_in | entity | 1.00 |
| CASP3 | data_in | entity | 1.00 |
| CCL2 | data_in | entity | 1.00 |
| CLU | data_in | entity | 1.00 |
| CR1 | data_in | entity | 1.00 |
| CX3CR1 | data_in | entity | 1.00 |
| Calcium signaling | data_in | entity | 1.00 |
| Camera-type eye development | data_in | entity | 1.00 |
| Chemokine signaling | data_in | entity | 1.00 |
| Cholesterol metabolic process | data_in | entity | 1.00 |
| HLA-DRB1 | data_in | entity | 1.00 |
| HTR2A | data_in | entity | 1.00 |
| IFITM3 | data_in | entity | 1.00 |
| Innate immune sensing | data_in | entity | 1.00 |
| Interferon gamma signaling | data_in | entity | 1.00 |
| Interferon signaling | data_in | entity | 1.00 |
| Negative regulation of apoptosis | data_in | entity | 1.00 |
| PICALM | data_in | entity | 1.00 |
| PLCG2 | data_in | entity | 1.00 |
| PTK2B | data_in | entity | 1.00 |
| Positive regulation of apoptosis | data_in | entity | 1.00 |
| SORL1 | data_in | entity | 1.00 |
| SPI1 | data_in | entity | 1.00 |
| STAT3 | data_in | entity | 1.00 |
| Serotonergic synapse | data_in | entity | 1.00 |
| TREM2 | data_in | entity | 1.00 |
| TYROBP | data_in | entity | 1.00 |
| Apoptosis | data_in | pathway | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Apoptosis | provides_data_for | pathway | 1.00 |
| ABCA7 | provides_data_for | entity | 1.00 |
| AP2A1 | provides_data_for | entity | 1.00 |
| APOE | provides_data_for | entity | 1.00 |
| ATAD3A | provides_data_for | entity | 1.00 |
| Antigen processing and presentation | provides_data_for | entity | 1.00 |
| BCL2L11 | provides_data_for | entity | 1.00 |
| BIN1 | provides_data_for | entity | 1.00 |
| CAMK4 | provides_data_for | entity | 1.00 |
| CASP3 | provides_data_for | entity | 1.00 |
| CCL2 | provides_data_for | entity | 1.00 |
| CLU | provides_data_for | entity | 1.00 |
| CR1 | provides_data_for | entity | 1.00 |
| CX3CR1 | provides_data_for | entity | 1.00 |
| Calcium signaling | provides_data_for | entity | 1.00 |
| Camera-type eye development | provides_data_for | entity | 1.00 |
| Chemokine signaling | provides_data_for | entity | 1.00 |
| Cholesterol metabolic process | provides_data_for | entity | 1.00 |
| HLA-DRB1 | provides_data_for | entity | 1.00 |
| HTR2A | provides_data_for | entity | 1.00 |
| IFITM3 | provides_data_for | entity | 1.00 |
| Innate immune sensing | provides_data_for | entity | 1.00 |
| Interferon gamma signaling | provides_data_for | entity | 1.00 |
| Interferon signaling | provides_data_for | entity | 1.00 |
| Negative regulation of apoptosis | provides_data_for | entity | 1.00 |
| PICALM | provides_data_for | entity | 1.00 |
| PLCG2 | provides_data_for | entity | 1.00 |
| PTK2B | provides_data_for | entity | 1.00 |
| Positive regulation of apoptosis | provides_data_for | entity | 1.00 |
| SORL1 | provides_data_for | entity | 1.00 |
| SPI1 | provides_data_for | entity | 1.00 |
| STAT3 | provides_data_for | entity | 1.00 |
| Serotonergic synapse | provides_data_for | entity | 1.00 |
| TREM2 | provides_data_for | entity | 1.00 |
| TYROBP | provides_data_for | entity | 1.00 |
| Endocytosis | provides_data_for | pathway | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DS-DB4A006EA647 in their description or question text
No additional research found