concept

SONIC HEDGEHOG

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SONIC HEDGEHOG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

48Connections

1Hypotheses

0Analyses

0Outgoing

48Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	SONIC HEDGEHOG
Related Diseases	cancer, Prostate Cancer
Related Pathways	Hedgehog

Pathway Diagram

graph TD
    SONIC_HEDGEHOG["SONIC HEDGEHOG"]
    SMO["SMO"] -->|"target for"| SONIC_HEDGEHOG
    NEURON["NEURON"] -->|"activates"| SONIC_HEDGEHOG
    SHH["SHH"] -->|"activates"| SONIC_HEDGEHOG
    Prostate_Cancer["Prostate Cancer"] -->|"target for"| SONIC_HEDGEHOG
    PARKINSON["PARKINSON"] -->|"activates"| SONIC_HEDGEHOG
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"] -->|"activates"| SONIC_HEDGEHOG
    Parkinson["Parkinson"] -->|"activates"| SONIC_HEDGEHOG
    Als["Als"] -->|"activates"| SONIC_HEDGEHOG
    CANCER["CANCER"] -->|"target for"| SONIC_HEDGEHOG

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (48)

Source	Relation	Type	Str
SHH	associated_with	gene	0.80
SMO	therapeutic_target	gene	0.70
SHH	activates	gene	0.70
NEURON	activates	gene	0.70
JNK	therapeutic_target	gene	0.60
P38	therapeutic_target	gene	0.60
AKT	activates	gene	0.60
PTCH1	activates	gene	0.60
BAD	therapeutic_target	gene	0.60
DES	therapeutic_target	gene	0.60
CANCER	associated_with	gene	0.60
Prostate Cancer	therapeutic_target	disease	0.60
Cancer	associated_with	disease	0.60
PARKINSON	activates	gene	0.60
PARKINSON'S DISEASE	activates	gene	0.60
Parkinson	activates	disease	0.60
Als	activates	disease	0.60
CANCER	therapeutic_target	gene	0.60
Pancreatic Cancer	therapeutic_target	disease	0.60
Cancer	therapeutic_target	disease	0.60
NATURAL COMPOUNDS	therapeutic_target	gene	0.60
C-JUN	therapeutic_target	gene	0.60
ERK	activates	gene	0.60
NF-ΚB	activates	gene	0.60
INFLAMMATION	therapeutic_target	gene	0.60
JAK	activates	gene	0.60
Autoimmune	therapeutic_target	disease	0.60
Rheumatoid Arthritis	therapeutic_target	disease	0.60
Inflammation	therapeutic_target	disease	0.60
SHH	regulates	gene	0.60
PI3K	activates	gene	0.60
JUN	therapeutic_target	gene	0.60
ASTROCYTES	associated_with	gene	0.60
GENES	activates	gene	0.60
ASTROCYTE	associated_with	gene	0.60
SYNAPSE	activates	gene	0.60
ERBB2	treats	gene	0.60
DNA	associated_with	gene	0.60
GENE MUTATIONS	associated_with	gene	0.60
Tumor	treats	disease	0.60
Als	treats	disease	0.60
Medulloblastoma	associated_with	disease	0.60
cancer	regulates	disease	0.50
Prostate Cancer	regulates	disease	0.50
cancer	interacts_with	disease	0.50
Hedgehog	interacts_with	pathway	0.50
Prostate Cancer	interacts_with	disease	0.50
Hedgehog	regulates	pathway	0.50

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
Sonic hedgehog pathway compartmentalization as quantitative	0.485	neuroscience	How can subcellular compartmentalization

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SONIC HEDGEHOG in their description or question text

No additional research found