concept

PSME3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PSME3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

73Connections

0Hypotheses

0Analyses

50Outgoing

21Incoming

0Experiments

0Debates

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💡 Concept Info

Name	PSME3
Key Genes/Proteins	AND, APOPTOSIS, AUTOPHAGY, BAD, BID, Cytokine
Related Diseases	Als, ALS, Ferroptosis
Related Pathways	Apoptosis, apoptosis pathway, Autophagy, autophagy pathway

Pathway Diagram

graph TD
    PSME3["PSME3"]
    PSME3 -->|"involved_in"| Proteasomal_Antimicrobial_Resp["Proteasomal Antimicrobial Responses"]
    PSME3 -->|"target for"| Parkinson["Parkinson"]
    PSME3 -->|"expressed in"| Ferroptosis["Ferroptosis"]
    PSME3 -->|"expressed in"| Als["Als"]
    PSME3 -->|"target for"| TLR2["TLR2"]
    PSME3 -->|"target for"| IL_1["IL-1"]
    PSME3 -->|"target for"| IL_17["IL-17"]
    PSME3 -->|"target for"| PARKINSON["PARKINSON"]
    BID["BID"] -->|"expressed in"| PSME3
    IL_17 -->|"target for"| PSME3
    PPP1CB["PPP1CB"] -->|"expressed in"| PSME3
    IL_1 -->|"target for"| PSME3
    TLR2 -->|"target for"| PSME3
    PARKINSON -->|"target for"| PSME3

Outgoing (52)

Target	Relation	Type	Str
Proteasomal Antimicrobial Response	involved_in	process	0.90
Proteasomal Antimicrobial Responses	involved_in	process	0.80
Antimicrobial Response	involved_in	process	0.80
proteasomal antimicrobial response	involved_in	process	0.80
ALS	associated_with	disease	0.65
Parkinson	associated_with	disease	0.65
Inflammation	associated_with	disease	0.65
Ferroptosis	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
Parkinson	therapeutic_target	disease	0.65
Als	associated_with	disease	0.65
PARKINSON	therapeutic_target	gene	0.60
IL-1	therapeutic_target	gene	0.60
TLR2	therapeutic_target	gene	0.60
Immune Response	therapeutic_target	pathway	0.60
apoptosis pathway	participates_in	pathway	0.60
autophagy pathway	participates_in	pathway	0.60
ferroptosis	participates_in	pathway	0.60
IL-17	therapeutic_target	gene	0.60
BID	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
PPP1CB	associated_with	gene	0.60
IL-17	associated_with	gene	0.60
TLR2	associated_with	gene	0.60
AND	associated_with	gene	0.60
MTOR	associated_with	gene	0.60
TFRC	associated_with	gene	0.60
IFN	associated_with	gene	0.60
FERROPTOSIS	associated_with	gene	0.60
APOPTOSIS	associated_with	gene	0.60
IFN-Γ	associated_with	gene	0.60
Autophagy	expressed_in	pathway	0.60
BAD	associated_with	gene	0.60
Mtor	expressed_in	pathway	0.60
Autophagy	associated_with	pathway	0.60
Immune Response	associated_with	pathway	0.60
Mtor	associated_with	pathway	0.60
Ferroptosis	associated_with	pathway	0.60
Apoptosis	associated_with	pathway	0.60
MTOR	expressed_in	gene	0.60
FERROPTOSIS	expressed_in	gene	0.60
APOPTOSIS	expressed_in	gene	0.60
AUTOPHAGY	expressed_in	gene	0.60
TFRC	expressed_in	gene	0.60
LAMP2	expressed_in	gene	0.60
Apoptosis	expressed_in	pathway	0.60
Cytokine	therapeutic_target	protein	0.60
GENES	associated_with	gene	0.60
INFLAMMATION	associated_with	gene	0.60
LAMP2	associated_with	gene	0.60

Incoming (21)

Source	Relation	Type	Str
APOPTOSIS	associated_with	gene	0.60
MTOR	associated_with	gene	0.60
GENES	associated_with	gene	0.60
IL-17	associated_with	gene	0.60
LAMP2	associated_with	gene	0.60
IFN	associated_with	gene	0.60
PPP1CB	associated_with	gene	0.60
FERROPTOSIS	associated_with	gene	0.60
BID	associated_with	gene	0.60
IFN-Γ	associated_with	gene	0.60
TLR2	associated_with	gene	0.60
TFRC	associated_with	gene	0.60
BAD	associated_with	gene	0.60
INFLAMMATION	associated_with	gene	0.60
BID	expressed_in	gene	0.60
IL-17	therapeutic_target	gene	0.60
PPP1CB	expressed_in	gene	0.60
IL-1	therapeutic_target	gene	0.60
TLR2	therapeutic_target	gene	0.60
PARKINSON	therapeutic_target	gene	0.60
AUTOPHAGY	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PSME3 in their description or question text

No additional research found