gene

apoa2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about apoa2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

40Connections

0Hypotheses

0Analyses

27Outgoing

13Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	APOA2
Full Name	Apolipoprotein A2
Chromosome	1q23.3
Function	The APOA2 gene encodes Apolipoprotein A2, the second most abundant apolipoprotein in high-density lipoprotein (HDL) particles.
Molecular Weight	17 kDa
Amino Acids	77 aa
UniProt ID	APOA2
NCBI Gene ID	336
Ensembl ID	ENSG00000158874
OMIM	107670
GeneCards	APOA2
Human Protein Atlas	APOA2
Hypertriglyceridemia	APOA2 affects triglyceride metabolism
Associated Diseases	Parkinson, Als, Ms, neurodegeneration
Databases	GeneCards HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

APOA2 Gene

gene · 523 words

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Pathway Diagram

graph TD
    APOA2["APOA2"]
    APOA2 -.biomarker for.-> Carcinoma["Carcinoma"]
    APOA2 -.biomarker for.-> Tumor["Tumor"]
    APOA2 -->|"regulates"| Cardiovascular["Cardiovascular"]
    APOA2 -->|"regulates"| Diabetes["Diabetes"]
    APOA2 -->|"regulates"| Metabolic_Syndrome["Metabolic Syndrome"]
    APOA2 -->|"regulates"| Als["Als"]
    APOA2 -->|"regulates"| Atherosclerosis["Atherosclerosis"]
    APOA2 -->|"regulates"| Inflammation["Inflammation"]
    OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"regulates"| APOA2
    TCF7L2["TCF7L2"] -->|"interacts"| APOA2
    IL_6["IL-6"] -->|"interacts"| APOA2
    INFLAMMATION["INFLAMMATION"] -->|"regulates"| APOA2
    GENES["GENES"] -->|"regulates"| APOA2

Outgoing (27)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:APOA2	data_in	dataset_row	0.00
Ms	associated_with	disease	0.65
Parkinson	associated_with	disease	0.65
Als	associated_with	disease	0.65
Carcinoma	biomarker_for	disease	0.65
Cardiovascular	regulates	disease	0.65
Tumor	biomarker_for	disease	0.65
Metabolic Syndrome	regulates	disease	0.65
Als	regulates	disease	0.65
Atherosclerosis	regulates	disease	0.65
Inflammation	regulates	disease	0.65
Diabetes	regulates	disease	0.65
Cholesterol	associated_with	pathway	0.60
PARKINSON'S DISEASE	associated_with	gene	0.60
PARKINSON	associated_with	gene	0.60
Oxidative Stress	regulates	pathway	0.60
LGALS3	associated_with	gene	0.60
CSNK2A1	associated_with	gene	0.60
LDLR	associated_with	gene	0.60
APOC2	associated_with	gene	0.60
MCC	associated_with	gene	0.60
CAT	associated_with	gene	0.60
APOA1	associated_with	gene	0.60
STX4	associated_with	gene	0.60
HSPB1	associated_with	gene	0.60
NEURODEGENERATIVE DISORDERS	associated_with	gene	0.60
Lipid Metabolism	associated_with	pathway	0.60

Incoming (13)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:APOA2	data_in	dataset_row	0.00
STX4	associated_with	gene	0.60
LDLR	associated_with	gene	0.60
LGALS3	associated_with	gene	0.60
PARKINSON'S DISEASE	associated_with	gene	0.60
OXIDATIVE STRESS	regulates	gene	0.60
IL-6	interacts_with	gene	0.60
INFLAMMATION	regulates	gene	0.60
GENES	regulates	gene	0.60
TCF7L2	interacts_with	gene	0.60
APOE4	associated_with	gene	0.60
ACOX1	associated_with	gene	0.60
HSPB1	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning apoa2 in their description or question text

No additional research found