gene 649 words KG: VPS13C
Contents

VPS13C Gene - Vacuolar Protein Sorting 13 Homolog C

🧬 Gene Info
Gene SymbolVPS13C
Full NameVacuolar Protein Sorting 13 Homolog C
AliasesPage for VPS13C Gene
Chromosome15q22.31
FunctionVPS13C is a member of the VPS13 family of lipid-transfer proteins.
Molecular Weight395 kDa
Amino Acids100 aa
Exons77
PathwayscGAS-STING pathway
UniProt IDQ9UPQ0
NCBI Gene ID86728
Ensembl IDENSG00000129048
GeneCardsVPS13C
Human Protein AtlasVPS13C
Associated DiseasesAls, Alzheimer, Ms, Parkinson, Parkinson's disease
InteractionsATP13A2, DJ1, DNAJC6, FBXO7, GBA1, LRRK2
KG Connections70 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Membrane Cholesterol Gradient Modulators
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (15)

Parkinson Basal Ganglia Circuit
circuit · KG edge: associated_with
GBA1 (Redirect)
redirect · KG edge: associated_with
PINK1 (PTEN-Induced Kinase 1)
entity · KG edge: associated_with
ATP13A2 — ATPase Cation Transporting 13A2
gene · KG edge: associated_with
ATP1A3 Gene - Sodium-Potassium ATPase Alpha 3
gene · KG edge: associated_with

Knowledge Graph (12 edges)

VPS13C encodes lipid transfer protein
VPS13C activates mitochondrial DNA accumulation
VPS13C associated_with BNIP3L
VPS13C associated_with MAP1LC3B
GCH1 associated_with VPS13C
VPS35 associated_with VPS13C
GBA1 associated_with VPS13C
TARDBP associated_with VPS13C
PARK7 associated_with VPS13C
DNAJC13 associated_with VPS13C

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