| Gene Symbol | ATP1A3 |
| Full Name | ATPase Na+/K+ Transporting Subunit Alpha 3 |
| Chromosome | 19q13.2 |
| Function | The Na+/K+-ATPase is an essential electrogenic pump that maintains the resting membrane potential and regulates cellular volume. |
| Molecular Weight | 111 kDa |
| UniProt ID | P13637 |
| NCBI Gene ID | 478 |
| Ensembl ID | ENSG00000105409 |
| OMIM | 168500 |
| GeneCards | ATP1A3 |
| Human Protein Atlas | ATP1A3 |
| Ion Transport | Active transport of 3 Na+ out and 2 K+ into neurons per ATP hydrolyzed |
| Membrane Potential | Establishes and maintains the neuronal resting membrane potential (-70 to -90 mV) |
| Secondary Transport | Powers secondary active transporters including glutamate transporters |
| Calcium Regulation | Indirectly affects calcium homeostasis through Na+/Ca2+ exchangers |
| Associated Diseases | Als, Alzheimer, Parkinson |
| Interactions | IL1B |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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