gene 720 words KG: TOMM40
Contents

TOMM40 Gene

🧬 Gene Info
Gene SymbolTOMM40
Full NameTranslocase of Outer Mitochondrial Membrane 40
Chromosome19q13.32
FunctionTOMM40 is the core component of the TOM complex, the primary gateway for protein import into mitochondria.
Molecular Weight38 kDa
PathwaysMitophagy
UniProt IDQ9NTU5
NCBI Gene ID219988
Ensembl IDENSG00000130254
OMIM608633
GeneCardsTOMM40
Human Protein AtlasTOMM40
Associated DiseasesAging, Alzheimer
InteractionsABCA7, AND, APOE, APOPTOSIS, BIN1, BRAIN INJURY
SciDEX HypothesesMitochondrial Proteostasis Hijacking
KG Connections90 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (11)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

ABCA7 (Redirect)
redirect · KG edge: interacts_with
Apoptosis in Neurodegeneration
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
Genes
index · KG edge: interacts_with
ATG12 — Autophagy Related 12
gene · KG edge: regulates

Knowledge Graph (12 edges)

CSNK2B regulates TOMM40
TOMM20 therapeutic_target TOMM40
UBB regulates TOMM40
UBC regulates TOMM40
LC3 regulates TOMM40
MAP1LC3B regulates TOMM40
TOMM40 regulates ATG12
TOMM40 regulates ULK1
TUFM inhibits TOMM40
TOMM40 inhibits TUFM

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)