gene 2,509 words KG: RIPK2
Contents

RIPK2 (Receptor-Interacting Serine/Threonine-Protein Kinase 2)

🧬 Gene Info
Gene SymbolRIPK2
Full NameReceptor-Interacting Serine/Threonine Kinase 2
Chromosome8q21.3
Protein TypeSerine/Threonine Kinase
Functionis a critical serine/threonine kinase that serves as the primary signaling adaptor for NOD1 and NOD2 pattern recognition receptors.
Molecular Weight61 kDa
Amino Acids540 aa
PathwaysNF-κB, MAPK, MAPK signaling
UniProt IDQ9Y2K6
NCBI Gene ID8767
Ensembl IDENSG00000137275
OMIM603614
GeneCardsRIPK2
Human Protein AtlasRIPK2
Associated DiseasesAlzheimer, Amyotrophic Lateral Sclerosis, Cancer, Colorectal Cancer, IBD, Inflammatory Bowel Disease
Known Drugs/Compoundsrapamycin
InteractionsAKT, AKT1, ALS, ALZHEIMER, amyotrophic lateral sclerosis, APOPTOSIS
KG Connections319 knowledge graph edges
DatabasesGeneCardsHPASTRING

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