gene 841 words KG: PIK3R1
Contents

PIK3R1 Gene

🧬 Gene Info
Gene SymbolPIK3R1
Full NamePhosphoinositide-3-Kinase Regulatory Subunit 1
AliasesPIK3R1 p85α regulatory subunit of PI3K
Chromosome5q13.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight85 kDa
Amino Acids724 aa
PathwaysPI3K, mTOR, mtor, PI3K pathway
GeneCardsPIK3R1
Human Protein AtlasPIK3R1
Associated DiseasesAging, Als, Alzheimer, Cancer, Fibrosis
InteractionsAGING, Akt, AKT, AKT1, ALZHEIMER, AND
KG Connections373 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88
APOE-Dependent Autophagy Restoration
Score: 0.85
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.78
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (8)

Apoptosis in Neurodegeneration
entity · KG edge: therapeutic_target
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: regulates
ABCG1 Gene
gene · KG edge: expressed_in
AKT1 Gene
gene · KG edge: activates
AKT3 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

PIK3R1 regulates adipocyte function
IKBKB biomarker_for PIK3R1
PIK3R1 biomarker_for HDAC2
BNIP3 regulates PIK3R1
BCL2 regulates PIK3R1
CTSL regulates PIK3R1
FOXO3 therapeutic_target PIK3R1
PIK3R1 regulates BECN1
PIK3R1 regulates STAT3
PIK3R1 regulates CTSB

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