gene 583 words KG: IKBKB
Contents

IKBKB Gene

🧬 Gene Info
Gene SymbolIKBKB
Full NameIκB Kinase Beta
Chromosome8p11.21
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight87 kDa
Amino Acids756 aa
Exons22 coding exons
PathwaysNF-κB, NF-κB signaling
UniProt IDO14920
NCBI Gene ID3551
Ensembl IDENSG00000111640
GeneCardsIKBKB
Human Protein AtlasIKBKB
Transcript~2.8 kb mRNA
Associated DiseasesAls, Autoimmune, Ms, Rheumatoid Arthritis
InteractionsAND, AUTOPHAGY, BECN1, CANCER, CHUK, DSDNA
KG Connections152 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
AKT1 Gene
gene · KG edge: associated_with
BAG3 Gene
gene · KG edge: expressed_in
BCL2L1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

IKBKB inhibits MPXV
CHUK inhibits IKBKB
GAIN inhibits IKBKB
MTOR inhibits IKBKB
IKBKB inhibits GAIN
IKBKB inhibits MTOR
IKBKB inhibits CHUK
P38 activates IKBKB
IL1B activates IKBKB
PRDX1 activates IKBKB

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