gene 963 words KG: FGF18
Contents

FGF18 Gene

🧬 Gene Info
Gene SymbolFGF18
Full NameFibroblast Growth Factor 18
Chromosome5q33.1
Functionis a member of the fibroblast growth factor (FGF) family that plays important roles in development, tissue repair, and nervous system function.
Primary Expressionvarious tissues during development, with highest expression in bone, lung, and brain
Amino Acids207 aa
PathwaysMAPK
UniProt ID[O76093](https://www.uniprot.org/uniprot/O76093)
Ensembl IDENSG00000156427
GeneCardsFGF18
Human Protein AtlasFGF18
MAPK/ERK pathwayRegulates cell proliferation and differentiation
PI3K/Akt pathwayPromotes cell survival
PLCγ pathwayModulates calcium signaling
Subventricular zoneMaintains neural stem cell pools
Associated Diseasesneurodegeneration
InteractionsKEAP1, NRF2, UBIQUITIN
KG Connections103 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: regulates
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: therapeutic_target
ALDH1A1 Gene
gene · KG edge: therapeutic_target
APC Gene
gene · KG edge: therapeutic_target
ATF3 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

FGF20 therapeutic_target FGF18
BRG1 therapeutic_target FGF18
NRCAM therapeutic_target FGF18
NOTCH2 therapeutic_target FGF18
EP300 therapeutic_target FGF18
CTNNB1 therapeutic_target FGF18
NEUROD1 therapeutic_target FGF18
MYC therapeutic_target FGF18
VEGFA therapeutic_target FGF18
FOXM1 therapeutic_target FGF18

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