gene 816 words KG: GABARAPL1
Contents

GABARAPL1 — GABA Type A Receptor Associated Protein Like 1

🧬 Gene Info
Gene SymbolGABARAPL1
Full NameGABA Type A Receptor Associated Protein Like 1
Chromosome12p13.2
Functionis a gene located on chromosome 12p13.
Primary Expressionthe brain and plays essential roles in autophagy, intracellular trafficking, and cellular stress responses[@legrand2021]
Molecular Weight14 kDa
Amino Acids117 aa
PathwaysGlycophagy
UniProt IDQ9Y4L5
NCBI Gene ID23710
Ensembl IDENSG00000139218
OMIM607420
GeneCardsGABARAPL1
Human Protein AtlasGABARAPL1
PhosphorylationGABARAPL1 can be phosphorylated, modulating its interaction with autophagy receptors
Associated DiseasesAls, Cancer, Ms, Tumor
Known Drugs/Compoundsrapamycin
InteractionsABCA1, ACSL5, Actin, AKT, AND, ASTROCYTES
KG Connections232 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (13)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (12)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

See Also (9)

Astrocytes
cell · KG edge: inhibits
Astrocytes
entity · KG edge: inhibits
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: regulates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with

Knowledge Graph (12 edges)

GABARAP associated_with GABARAPL1
VAMP8 associated_with GABARAPL1
RTN3 associated_with GABARAPL1
LAMP2 associated_with GABARAPL1
DNM1L associated_with GABARAPL1
ULK1 associated_with GABARAPL1
LC3 associated_with GABARAPL1
MTOR associated_with GABARAPL1
RAB2A associated_with GABARAPL1
VAMP7 associated_with GABARAPL1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)