gene 2,794 words KG: EEF2
Contents

Eukaryotic Translation Elongation Factor 2 (EEF2)

🧬 Gene Info
Gene SymbolEEF2
Full NameEukaryotic Translation Elongation Factor 2 (EEF2)
Chromosome19p13.3
Protein TypeGene
Functionis a GTP-dependent molecular motor that catalyzes the translocation step of protein synthesis, moving the peptidyl-tRNA from the A-site to the P-site of the ribosome with each elongation cycle.
Molecular Weight95.4 kDa
Amino Acids739 aa
PathwaysMtor, Synaptic Plasticity, Wnt
GeneCardsEEF2
Human Protein AtlasEEF2
Associated DiseasesAls, Cardiovascular, Ischemia, Ms
InteractionsACTB, AGING, AKT, AND, ANG, Bdnf
KG Connections152 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

APOE-Dependent Autophagy Restoration
Score: 0.88
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

Synaptic plasticity and protein expression analysis in mPFC
exploratory · proposed · Score: 0.85
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (12)

ACTB Gene
gene · KG edge: interacts_with
ANG — Angiogenin
gene · KG edge: activates
ARID1A
gene · KG edge: associated_with
BDNF Gene
gene · KG edge: activates
BNIP3 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

EEF2 activates PKC
EEF2 activates TNF
P38 activates EEF2
EEF2 activates AKT
AKT activates EEF2
EEF2 activates P38
EEF2 inhibits REST
CD4 interacts_with EEF2
MAPK3 interacts_with EEF2
ZAP70 interacts_with EEF2

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