| Gene Symbol | CXCL8 |
| Chromosome | 4q13.3 |
| Protein Family | CXC chemokine family (ELR+) |
| Function | is a protein encoded by the CXCL8 gene. |
| Primary Expression | the central nervous system, influencing neurotransmitter release and synaptic plasticity[@biber2002] |
| Subcellular Localization | Secreted, extracellular |
| Molecular Weight | 8 kDa |
| Amino Acids | 99 aa |
| Exons | 4 |
| Pathways | NF-κB |
| UniProt ID | [P10145](https://www.uniprot.org/uniprot/P10145) |
| NCBI Gene ID | 3576 |
| GeneCards | CXCL8 |
| Human Protein Atlas | CXCL8 |
| NF-κB sites | Critical for cytokine-induced expression |
| Associated Diseases | ALS, Alzheimer, Depression, Fibrosis, Inflammation, Ms |
| Known Drugs/Compounds | rapamycin |
| Interactions | Actin, adcy2, ADCY2, AGING, AKT, ALZHEIMER |
| KG Connections | 488 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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