Contents

CSF1 Gene

🧬 Gene Info

Gene Symbol	CSF1
Chromosome	1p13.3
Function	is a disulfide-bonded homodimer of approximately 60 kDa.
Primary Expression	neurons[@wang2018]
Molecular Weight	60 kDa
Amino Acids	554 aa
Exons	11
Pathways	PI3K, MAPK
Ensembl ID	ENSG00000184371
GeneCards	CSF1
Human Protein Atlas	CSF1
Isoform 1 (canonical)	554 amino acids, secreted soluble protein
Isoform 2	Truncated, membrane-bound form
Isoform 3	Alternative start site variant
N-terminal signal peptide	Directs secretion
Associated Diseases	Melanoma, multiple sclerosis, Tumor
Interactions	ACTB, AGING, AKT, AMPK, AND, APOPTOSIS
KG Connections	158 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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Knowledge Graph

STAT1 activates CSF1

CSF1 activates BAX

CSF1 activates DDX58

DDX58 activates CSF1

BAX activates CSF1

CSF1 activates STAT1

SOX2 activates CSF1

ATF2 activates CSF1

CSF1 activates BNIP3L

CSF1 activates NEAT1