gene 615 words KG: CCL20
Contents

CCL20 Gene

🧬 Gene Info
Gene SymbolCCL20
Chromosome2q36.3
Protein TypeChemokine
FunctionCCL20 has distinct functions in immune and nervous systems:
Primary ExpressionCCR6 is expressed on Th17 cells, regulatory T cells, B cells, and dendritic cells
Molecular Weight8 kDa
PathwaysPI3K, MAPK
NCBI Gene ID6384
GeneCardsCCL20
Human Protein AtlasCCL20
Associated DiseasesAls, Alzheimer, Autoimmune, Cancer, Carcinoma, Diabetes
Known Drugs/CompoundsIRN
InteractionsAND, C1QA, CANCER, CCR6, CEBPB, Chemokine
KG Connections155 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88
Complement C1q Mimetic Decoy Therapy
Score: 0.69
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68

Related Analyses (4)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Astrocytes
cell · KG edge: regulates
Astrocytes
entity · KG edge: regulates
ATF6 - Activating Transcription Factor 6
gene · KG edge: associated_with
BMP7 Gene (Bone Morphogenetic Protein 7)
gene · KG edge: associated_with
C1QA Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

IRN inhibits CCL20
MMP9 activates CCL20
IL6 activates CCL20
CCL20 activates TLR4
CCL20 activates MMP9
CCL20 activates IL6
CCL20 regulates STAT3
CCL20 regulates CX3CL1
CCL20 regulates CXCL10
CCL20 activates C1QA

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