concept

MT-ND4L

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MT-ND4L: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

49Connections

0Hypotheses

0Analyses

30Outgoing

19Incoming

0Experiments

0Debates

No summary available yet.

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💡 Concept Info

Name	MT-ND4L
Key Genes/Proteins	Actin, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOPTOSIS
Related Diseases	Alzheimer
Related Pathways	Akt, Apoptosis, Hippo Pathway

Pathway Diagram

graph TD
    MT_ND4L["MT-ND4L"]
    MT_ND4L -->|"regulates"| Alzheimer["Alzheimer"]
    MT_ND4L -->|"regulates"| Ms["Ms"]
    MT_ND4L -->|"regulates"| APOPTOSIS["APOPTOSIS"]
    MT_ND4L -->|"regulates"| OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    MT_ND4L -->|"regulates"| MST1["MST1"]
    MT_ND4L -->|"regulates"| Akt["Akt"]
    MT_ND4L -->|"regulates"| Mitochondrial_Function["Mitochondrial Function"]
    MT_ND4L -->|"regulates"| Apoptosis["Apoptosis"]
    MT_ND4L -->|"regulates"| Immune_Response["Immune Response"]
    MT_ND4L -->|"regulates"| Oxidative_Stress["Oxidative Stress"]
    PGC1_["PGC1alpha"] -->|"regulates"| MT_ND4L
    MST1 -->|"regulates"| MT_ND4L
    MT_ATP6["MT-ATP6"] -->|"regulates"| MT_ND4L
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"regulates"| MT_ND4L
    PI3K["PI3K"] -->|"regulates"| MT_ND4L
    HIPPO["HIPPO"] -->|"regulates"| MT_ND4L
    AKT["AKT"] -->|"regulates"| MT_ND4L
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"] -->|"regulates"| MT_ND4L
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"] -->|"regulates"| MT_ND4L
    MT_CO2["MT-CO2"] -->|"regulates"| MT_ND4L

Outgoing (30)

Target	Relation	Type	Str
Alzheimer	regulates	disease	0.65
Ms	regulates	disease	0.65
MST1	regulates	gene	0.60
Akt	regulates	pathway	0.60
Mitochondrial Function	regulates	pathway	0.60
Apoptosis	regulates	pathway	0.60
Immune Response	regulates	pathway	0.60
Oxidative Stress	regulates	pathway	0.60
APOPTOSIS	regulates	gene	0.60
Pi3K	regulates	pathway	0.60
OXIDATIVE STRESS	regulates	gene	0.60
ROS	regulates	gene	0.60
PI3K	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
HIPPO	regulates	gene	0.60
MITOCHONDRIAL DNA	regulates	gene	0.60
MT-ATP6	regulates	gene	0.60
GENES	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
MT-CO2	regulates	gene	0.60
AKT	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	regulates	gene	0.60
DNA	regulates	gene	0.60
ATP	regulates	gene	0.60
Hippo Pathway	regulates	pathway	0.60
RNA	regulates	gene	0.60
Actin	regulates	protein	0.60
Neuron	regulates	cell_type	0.60
Hippocampus	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55

Incoming (19)

Source	Relation	Type	Str
PGC1α	regulates	protein	0.70
MST1	regulates	protein	0.70
MT-ATP6	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
PI3K	regulates	gene	0.60
HIPPO	regulates	gene	0.60
AKT	regulates	gene	0.60
MITOCHONDRIAL DNA	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	regulates	gene	0.60
MT-CO2	regulates	gene	0.60
APOPTOSIS	regulates	gene	0.60
OXIDATIVE STRESS	regulates	gene	0.60
GENES	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
ROS	regulates	gene	0.60
AND	regulates	gene	0.60
ATP	regulates	gene	0.60
MST1	interacts_with	gene	0.50
MT-ATP6	interacts_with	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MT-ND4L in their description or question text

No additional research found