protein

MT-ATP6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MT-ATP6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

50Connections

0Hypotheses

0Analyses

31Outgoing

19Incoming

0Experiments

0Debates

Summary

MT-ATP6 is a protein involved in neurodegeneration research. Key relationships include: regulates. Associated with Alzheimer, Ms. Connected to 33 entities in the SciDEX knowledge graph.

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🔬 Protein Info

Gene Symbol	MT
Function	Cytochrome b is a key component of Complex III (ubiquinol-cytochrome c reductase), which catalyzes the transfer of electrons from ubiquinol to cytochrome c.
GeneCards	MT
Human Protein Atlas	MT
Interactions	MST1
KG Connections	50 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

MT-ATP6 Protein (ATP Synthase Subunit 6)

protein · 705 words

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Pathway Diagram

graph TD
    MT_ATP6["MT-ATP6"]
    Alzheimer{"Alzheimer"}
    MT_ATP6 -->|"regulates"| Alzheimer
    Ms{"Ms"}
    MT_ATP6 -->|"regulates"| Ms
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    MT_ATP6 -->|"regulates"| ALZHEIMER_S_DISEASE
    PI3K["PI3K"]
    MT_ATP6 -->|"regulates"| PI3K
    HIPPO["HIPPO"]
    MT_ATP6 -->|"regulates"| HIPPO
    AKT["AKT"]
    MT_ATP6 -->|"regulates"| AKT
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MT_ATP6 -->|"regulates"| MITOCHONDRIAL_DNA
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    MT_ATP6 -->|"regulates"| MITOCHONDRIAL_DYSFUNCTION
    MT_CO2["MT-CO2"]
    MT_ATP6 -->|"regulates"| MT_CO2
    MT_ND4L["MT-ND4L"]
    MT_ATP6 -->|"regulates"| MT_ND4L
    APOPTOSIS["APOPTOSIS"]
    MT_ATP6 -->|"regulates"| APOPTOSIS
    OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    MT_ATP6 -->|"regulates"| OXIDATIVE_STRESS
    PGC1_["PGC1alpha"]
    PGC1_ -->|"regulates"| MT_ATP6
    style MT_ATP6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (31)

Target	Relation	Type	Str
Alzheimer	regulates	disease	0.65
Ms	regulates	disease	0.65
HIPPO	regulates	gene	0.60
AKT	regulates	gene	0.60
MITOCHONDRIAL DNA	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	regulates	gene	0.60
MT-CO2	regulates	gene	0.60
MT-ND4L	regulates	gene	0.60
APOPTOSIS	regulates	gene	0.60
OXIDATIVE STRESS	regulates	gene	0.60
MST1	regulates	gene	0.60
Akt	regulates	pathway	0.60
Mitochondrial Function	regulates	pathway	0.60
Apoptosis	regulates	pathway	0.60
Immune Response	regulates	pathway	0.60
Oxidative Stress	regulates	pathway	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
Pi3K	regulates	pathway	0.60
PI3K	regulates	gene	0.60
Actin	regulates	protein	0.60
ALZHEIMER	regulates	gene	0.60
ROS	regulates	gene	0.60
GENES	regulates	gene	0.60
DNA	regulates	gene	0.60
ATP	regulates	gene	0.60
Hippo Pathway	regulates	pathway	0.60
Neuron	regulates	cell_type	0.60
AND	regulates	gene	0.60
Hippocampus	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55
MT-ND4L	interacts_with	concept	0.50

Incoming (19)

Source	Relation	Type	Str
PGC1α	regulates	protein	0.70
ALZHEIMER'S DISEASE	regulates	gene	0.60
AND	regulates	gene	0.60
MITOCHONDRIAL DYSFUNCTION	regulates	gene	0.60
GENES	regulates	gene	0.60
MT-ND4L	regulates	gene	0.60
ROS	regulates	gene	0.60
APOPTOSIS	regulates	gene	0.60
MST1	regulates	gene	0.60
OXIDATIVE STRESS	regulates	gene	0.60
PI3K	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
HIPPO	regulates	gene	0.60
MITOCHONDRIAL DNA	regulates	gene	0.60
RNA	regulates	gene	0.60
AKT	regulates	gene	0.60
MT-CO2	regulates	gene	0.60
ATP	regulates	gene	0.60
MST1	interacts_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MT-ATP6 in their description or question text

No additional research found