gene

grid2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about grid2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

39Connections

0Hypotheses

0Analyses

26Outgoing

13Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	GRID2
Full Name	Glutamate Ionotropic Receptor Delta Type Subunit 2
Protein Type	Receptor
Function	GRID2 (Glutamate Receptor Ionotropic Delta 2), also known as GluRδ2 or GluD2, is a member of the delta glutamate receptor family with critical roles in cerebellar function, synaptic plasticity, and mo
Molecular Weight	115 kDa
Ensembl ID	ENSG00000128283
GeneCards	GRID2
Human Protein Atlas	GRID2
Protein Kinase C (PKC)	Key mediator of LTD induction
CaMKII	Calcium/calmodulin-dependent protein kinase II
MAP1B	Microtubule-associated protein involved in synaptic plasticity
Shank2	Scaffold protein at postsynaptic密度
Associated Diseases	Als
Interactions	CANCER, ERK, GRIK3, NEURON, PDGFRA, RAS
KG Connections	39 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GRID2 — Glutamate Ionotropic Receptor Delta Type Subunit 2

gene · 1942 words

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Pathway Diagram

graph TD
    GRID2["GRID2"]
    GRID2 -->|"activates"| Cancer["Cancer"]
    GRID2 -->|"activates"| Tumor["Tumor"]
    GRID2 -->|"expressed in"| Schizophrenia["Schizophrenia"]
    GRID2 -->|"inhibits"| PDGFRA["PDGFRA"]
    GRID2 -->|"activates"| NEURON["NEURON"]
    GRID2 -->|"activates"| ERK["ERK"]
    GRID2 -->|"activates"| RAS["RAS"]
    GRID2 -->|"activates"| GRIK3["GRIK3"]
    GRIK3 -->|"activates"| GRID2
    ERK -->|"activates"| GRID2
    SRC["SRC"] -->|"activates"| GRID2
    GLUD1["GLUD1"] -->|"transports"| GRID2

Outgoing (26)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:GRID2	data_in	dataset_row	0.00
Als	associated_with	disease	0.65
Schizophrenia	expressed_in	disease	0.65
Cancer	activates	disease	0.65
Tumor	activates	disease	0.65
ERK	activates	gene	0.60
RAS	activates	gene	0.60
SYNAPSE	transports	gene	0.60
CANCER	activates	gene	0.60
GRIK3	activates	gene	0.60
SRC	activates	gene	0.60
NEURON	activates	gene	0.60
MAPK signaling	participates_in	pathway	0.60
MAPK7	expressed_in	gene	0.60
RIPK2	expressed_in	gene	0.60
UHRF1	expressed_in	gene	0.60
RIPK2	biomarker_for	gene	0.60
PDGFRA	inhibits	gene	0.60
GLUD2	transports	gene	0.60
GRID1	expressed_in	gene	0.60
CBLN2	expressed_in	gene	0.60
Rb	expressed_in	protein	0.60
MAP	expressed_in	gene	0.60
MAPK	expressed_in	gene	0.60
MRPS31	expressed_in	gene	0.60
necroptosis	participates_in	pathway	0.60

Incoming (13)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:GRID2	data_in	dataset_row	0.00
ABCA7	expressed_in	gene	0.60
ARF1	expressed_in	gene	0.60
ATG7	expressed_in	gene	0.60
E2F2	expressed_in	gene	0.60
ELAVL1	expressed_in	gene	0.60
ABCA7	biomarker_for	gene	0.60
G6PD	expressed_in	gene	0.60
E2F2	biomarker_for	gene	0.60
GLUD1	transports	gene	0.60
ERK	activates	gene	0.60
GRIK3	activates	gene	0.60
SRC	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning grid2 in their description or question text

No additional research found