Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about glud2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GLUD2 |
| Full Name | Glutamate Dehydrogenase 2 |
| Chromosome | 6q24.2 |
| Protein Family | Glu/Leu/Phe/Val dehydrogenase |
| Protein Type | Enzyme |
| Amino Acids | 505 aa |
| UniProt ID | P49448 |
| NCBI Gene ID | 2717 |
| Ensembl ID | ENSG00000198692 |
| OMIM | 138147 |
| GeneCards | GLUD2 |
| Human Protein Atlas | GLUD2 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, Huntington's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["GLUD2"]
N1["Als"]
N0 -->|"associated with"| N1
N2["Schizophrenia"]
N0 -->|"expressed in"| N2
N3["SYNAPSE"]
N0 -->|"transports"| N3
N4["GRID1"]
N0 -->|"transports"| N4
N5["CBLN2"]
N0 -->|"expressed in"| N5
N6["Rb"]
N0 -->|"expressed in"| N6
N7["GLUD1"]
N7 -->|"transports"| N0
N8["GRID2"]
N8 -->|"transports"| N0
N9["neurodegeneration"]
N0 -->|"implicated in"| N9
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
class N1 disease
class N2 disease
class N3 gene
class N4 gene
class N5 gene
class N6 protein
class N7 gene
class N8 gene| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:GLUD2 | data_in | dataset_row | 0.00 |
| Als | associated_with | disease | 0.65 |
| Schizophrenia | expressed_in | disease | 0.65 |
| SYNAPSE | transports | gene | 0.60 |
| GRID1 | transports | gene | 0.60 |
| CBLN2 | expressed_in | gene | 0.60 |
| Rb | expressed_in | protein | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:GLUD2 | data_in | dataset_row | 0.00 |
| GLUD1 | transports | gene | 0.60 |
| GRID2 | transports | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning glud2 in their description or question text
No additional research found