gene

GNA13

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GNA13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

55Connections

0Hypotheses

0Analyses

28Outgoing

27Incoming

0Experiments

0Debates

Summary

GNA13 is a gene implicated in neurodegeneration research. Key relationships include: expressed in, associated with, implicated in. Associated with Als, Lymphoma, Schizophrenia. Connected to 23 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	GNA13
Full Name	G Protein Subunit Alpha 13
Chromosome	17q21.31
Protein Family	Gq alpha subunit family
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	neurons where it participates in synaptic transmission
Molecular Weight	~43 kDa
Amino Acids	377 aa
Exons	11
UniProt ID	[Q9UQF2](https://www.uniprot.org/uniprot/Q9UQF2)
Ensembl ID	ENSG00000127616
GeneCards	GNA13
Human Protein Atlas	GNA13
Gene Location	Chromosome 17q21.31
Exon Count	11 exons spanning approximately 10 kb
Associated Diseases	Als, Schizophrenia
Interactions	AND, GJA1, ROCK2
KG Connections	55 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GNA13 Gene

gene · 584 words

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Pathway Diagram

graph TD
    GNA13["GNA13"]
    Lymphoma{"Lymphoma"}
    GNA13 -->|"expressed in"| Lymphoma
    Als{"Als"}
    GNA13 -->|"expressed in"| Als
    GNA13 -->|"associated with"| Als
    Schizophrenia{"Schizophrenia"}
    GNA13 -->|"associated with"| Schizophrenia
    REL["REL"]
    GNA13 -->|"expressed in"| REL
    PRDM1["PRDM1"]
    GNA13 -->|"expressed in"| PRDM1
    Apoptosis(["Apoptosis"])
    GNA13 -->|"expressed in"| Apoptosis
    Nf__b(["Nf-Kappab"])
    GNA13 -->|"expressed in"| Nf__b
    GNAI1["GNAI1"]
    GNA13 -->|"associated with"| GNAI1
    GNA12["GNA12"]
    GNA13 -->|"associated with"| GNA12
    neurodegeneration["neurodegeneration"]
    GNA13 -->|"implicated in"| neurodegeneration
    CDKN2A["CDKN2A"]
    CDKN2A -->|"expressed in"| GNA13
    TP53["TP53"]
    TP53 -->|"expressed in"| GNA13
    TET2["TET2"]
    TET2 -->|"expressed in"| GNA13
    MYD88["MYD88"]
    MYD88 -->|"expressed in"| GNA13
    KMT2D["KMT2D"]
    KMT2D -->|"expressed in"| GNA13
    NF__B["NF-KappaB"]
    NF__B -->|"expressed in"| GNA13
    STAT3["STAT3"]
    STAT3 -->|"expressed in"| GNA13
    DDX3X["DDX3X"]
    DDX3X -->|"expressed in"| GNA13
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"expressed in"| GNA13
    RB1["RB1"]
    RB1 -->|"expressed in"| GNA13
    GRIN2B["GRIN2B"]
    GRIN2B -->|"associated with"| GNA13
    DISC1["DISC1"]
    DISC1 -->|"associated with"| GNA13
    style GNA13 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (28)

Target	Relation	Type	Str
ROCK2	interacts_with	protein	0.80
Aging	biomarker_for	disease	0.65
Alzheimer	biomarker_for	disease	0.65
Als	associated_with	disease	0.65
Schizophrenia	associated_with	disease	0.65
Lymphoma	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
Aβ	biomarker_for	protein	0.60
PI3K	biomarker_for	gene	0.60
Apoptosis	expressed_in	pathway	0.60
Nf-Κb	expressed_in	pathway	0.60
Amyloid	biomarker_for	pathway	0.60
TAU	biomarker_for	gene	0.60
GJA1	activates	gene	0.60
ROCK2	activates	gene	0.60
Akt	biomarker_for	protein	0.60
GNAI1	associated_with	gene	0.60
GNA12	associated_with	gene	0.60
ROCK2	associated_with	gene	0.60
RNA	biomarker_for	gene	0.60
MAPK	biomarker_for	gene	0.60
Mapk	biomarker_for	pathway	0.60
AGING	biomarker_for	gene	0.60
ALZHEIMER	biomarker_for	gene	0.60
REL	expressed_in	gene	0.60
PRDM1	expressed_in	gene	0.60
GJA1	associated_with	gene	0.50
RNA	co_mentioned	gene	0.40

Incoming (27)

Source	Relation	Type	Str
AGING	biomarker_for	gene	0.60
ALZHEIMER	biomarker_for	gene	0.60
MAPK	biomarker_for	gene	0.60
TAU PATHOLOGY	biomarker_for	gene	0.60
RNA	biomarker_for	gene	0.60
AND	activates	gene	0.60
ALZHEIMER'S DISEASE	biomarker_for	gene	0.60
AMYLOID	biomarker_for	gene	0.60
TAU	biomarker_for	gene	0.60
CDKN2A	expressed_in	gene	0.60
TP53	expressed_in	gene	0.60
TET2	expressed_in	gene	0.60
MYD88	expressed_in	gene	0.60
KMT2D	expressed_in	gene	0.60
STAT3	expressed_in	gene	0.60
DDX3X	expressed_in	gene	0.60
RB1	expressed_in	gene	0.60
GJA1	biomarker_for	gene	0.60
GJA1	associated_with	gene	0.60
NF-ΚB	expressed_in	gene	0.60
APOPTOSIS	expressed_in	gene	0.60
GRIN2B	associated_with	gene	0.60
DISC1	associated_with	gene	0.60
ROCK2	activates	gene	0.60
GJA1	activates	gene	0.60
AKT	biomarker_for	gene	0.60
GJA1	co_mentioned	gene	0.40

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GNA13 in their description or question text

No additional research found