gene

CELF1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CELF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

92Connections

0Hypotheses

0Analyses

50Outgoing

39Incoming

0Experiments

0Debates

Summary

Page for CELF1 Gene

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🧬 Gene Info

Gene Symbol	CELF1
Full Name	CUGBP Elav-Like Family Member 1
Chromosome	11p11.2.
Function	is an RNA-binding protein encoded by the CELF1 gene located on chromosome 11p11.
Primary Expression	the nervous system: - Cerebral cortex: Neurons and glia - [Hippocampus](/brain-regions/hippocampus
Molecular Weight	52 kDa
Amino Acids	505 aa
UniProt ID	Q9UQF0
NCBI Gene ID	10658
Ensembl ID	ENSG00000131095
OMIM	601998
GeneCards	CELF1
Human Protein Atlas	CELF1
Associated Diseases	Als, Alzheimer, Cardiac Hypertrophy, Ms
Interactions	ABCA7, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOE, App
KG Connections	92 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CELF1 — AlphaFold Q9UQF0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CELF1 Gene

gene · 964 words

→

CELF1 Protein

protein · 1052 words

→

Pathway Diagram

graph TD
    CELF1["CELF1"]
    Cardiac_Hypertrophy{"Cardiac Hypertrophy"}
    CELF1 -->|"causes"| Cardiac_Hypertrophy
    Ms{"Ms"}
    CELF1 -->|"associated_with"| Ms
    Als{"Als"}
    CELF1 -->|"associated_with"| Als
    Alzheimer{"Alzheimer"}
    CELF1 -->|"associated_with"| Alzheimer
    AND["AND"]
    CELF1 -->|"associated_with"| AND
    GENES["GENES"]
    CELF1 -->|"associated_with"| GENES
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    CELF1 -->|"associated_with"| ALZHEIMER_S_DISEASE
    MEF2C["MEF2C"]
    CELF1 -->|"associated_with"| MEF2C
    PTK2B["PTK2B"]
    CELF1 -->|"associated_with"| PTK2B
    HLA["HLA"]
    CELF1 -->|"associated_with"| HLA
    FERMT2["FERMT2"]
    CELF1 -->|"associated_with"| FERMT2
    RIN3["RIN3"]
    CELF1 -->|"associated_with"| RIN3
    ZCWPW1["ZCWPW1"]
    CELF1 -->|"associated_with"| ZCWPW1
    PLD3["PLD3"]
    PLD3 -->|"associated_with"| CELF1
    ABCA7["ABCA7"]
    ABCA7 -->|"associated_with"| CELF1

Outgoing (53)

Target	Relation	Type	Str
Cardiac Hypertrophy	causes	disease	0.80
Ms	associated_with	disease	0.65
Als	associated_with	disease	0.65
Alzheimer	associated_with	disease	0.65
Alzheimer	activates	disease	0.65
ALS	activates	disease	0.65
Als	activates	disease	0.65
RIN3	associated_with	gene	0.60
ZCWPW1	associated_with	gene	0.60
LNCRNA	activates	gene	0.60
ALZHEIMER	activates	gene	0.60
RNA	activates	gene	0.60
ALZHEIMER	associated_with	gene	0.60
Lipid Metabolism	associated_with	pathway	0.60
Immune Response	associated_with	pathway	0.60
MEF2C	associated_with	gene	0.60
App	associated_with	protein	0.60
PTK2B	associated_with	gene	0.60
FERMT2	associated_with	gene	0.60
ABCA7	activates	gene	0.60
CASS4	activates	gene	0.60
EPHA1	activates	gene	0.60
CLU	activates	gene	0.60
BIN1	activates	gene	0.60
CD33	activates	gene	0.60
CD2AP	activates	gene	0.60
Rb	activates	protein	0.60
HLA	interacts_with	gene	0.60
MS4A	interacts_with	gene	0.60
ZCWPW1	interacts_with	gene	0.60
PTK2B	activates	gene	0.60
PPAR	activates	gene	0.60
SORL1	interacts_with	gene	0.60
APOE	activates	gene	0.60
CLU	interacts_with	gene	0.60
CR1	interacts_with	gene	0.60
EPHA1	interacts_with	gene	0.60
FERMT2	interacts_with	gene	0.60
INPP5D	interacts_with	gene	0.60
MEF2C	interacts_with	gene	0.60
NME8	interacts_with	gene	0.60
PICALM	interacts_with	gene	0.60
PTK2B	interacts_with	gene	0.60
RIN3	interacts_with	gene	0.60
SLC24A4	interacts_with	gene	0.60
HLA	associated_with	gene	0.60
AND	associated_with	gene	0.60
Ras	activates	protein	0.60
App	activates	protein	0.60
GENES	associated_with	gene	0.60

Incoming (39)

Source	Relation	Type	Str
ZCWPW1	activates	gene	0.60
FERMT2	activates	gene	0.60
ABCA7	interacts_with	gene	0.60
BIN1	interacts_with	gene	0.60
CASS4	interacts_with	gene	0.60
CD2AP	interacts_with	gene	0.60
CD33	interacts_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
RNA	activates	gene	0.60
AND	activates	gene	0.60
ALZHEIMER'S DISEASE	activates	gene	0.60
LNCRNA	activates	gene	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
PLD3	associated_with	gene	0.60
ABCA7	associated_with	gene	0.60
SORL1	associated_with	gene	0.60
PICALM	associated_with	gene	0.60
CR1	associated_with	gene	0.60
TREM2	associated_with	gene	0.60
CASS4	associated_with	gene	0.60
CD33	associated_with	gene	0.60
NME8	associated_with	gene	0.60
BIN1	associated_with	gene	0.60
CD2AP	associated_with	gene	0.60
INPP5D	associated_with	gene	0.60
EPHA1	associated_with	gene	0.60
CLU	associated_with	gene	0.60
ABCA7	activates	gene	0.60
APOE	activates	gene	0.60
CD2AP	activates	gene	0.60
EPHA1	activates	gene	0.60
CLU	activates	gene	0.60
BIN1	activates	gene	0.60
CASS4	activates	gene	0.60
CD33	activates	gene	0.60
PTK2B	activates	gene	0.60
GENES	activates	gene	0.60
ALZHEIMER	activates	gene	0.60
late	activates	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CELF1 in their description or question text

No additional research found