gene 964 words KG: CELF1
Contents

CELF1 Gene

🧬 Gene Info
Gene SymbolCELF1
Full NameCUGBP Elav-Like Family Member 1
Chromosome11p11.2.
Functionis an RNA-binding protein encoded by the CELF1 gene located on chromosome 11p11.
Primary Expressionthe nervous system: - Cerebral cortex: Neurons and glia - [Hippocampus](/brain-regions/hippocampus
Molecular Weight52 kDa
Amino Acids505 aa
UniProt IDQ9UQF0
NCBI Gene ID10658
Ensembl IDENSG00000131095
OMIM601998
GeneCardsCELF1
Human Protein AtlasCELF1
Associated DiseasesAls, Alzheimer, Cardiac Hypertrophy, Ms
InteractionsABCA7, ALZHEIMER, ALZHEIMER'S DISEASE, APOE, App, BIN1
KG Connections90 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (13)

CYP46A1 Overexpression Gene Therapy
Score: 0.95
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (4)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

ABCA7 (Redirect)
redirect · KG edge: activates
BIN1 — Bridging Integrator 1
gene · KG edge: activates
CASS4 — Cas Scaffold Protein Family Member 4
gene · KG edge: activates
CD2AP Gene — CD2-Associated Protein
gene · KG edge: activates
CLU — Clusterin (Apolipoprotein J)
gene · KG edge: activates

Knowledge Graph (12 edges)

CELF1 causes Cardiac Hypertrophy
PLD3 associated_with CELF1
ABCA7 associated_with CELF1
SORL1 associated_with CELF1
PICALM associated_with CELF1
CR1 associated_with CELF1
TREM2 associated_with CELF1
CASS4 associated_with CELF1
CD33 associated_with CELF1
NME8 associated_with CELF1

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