Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ATG9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ATG9 |
| Key Genes/Proteins | APOPTOSIS, ATG, ATG1, ATG12, ATG41, ATG5 |
| Related Diseases | Als, Bacterial Infection |
| Related Pathways | Apoptosis, Autophagy |
Knowledge base pages for this entity
graph TD
ATG9["ATG9"]
ATG9 -->|"activates"| autophagosome_formation["autophagosome formation"]
ATG9 -->|"regulates"| autophagosome_biogenesis["autophagosome biogenesis"]
ATG9 -->|"interacts"| Infection["Infection"]
ATG9 -->|"interacts"| Bacterial_Infection["Bacterial Infection"]
ATG9 -->|"interacts"| Als["Als"]
ATG9 -->|"regulates"| Ms["Ms"]
ATG9 -->|"regulates"| Tumor["Tumor"]
ATG41["ATG41"] -->|"interacts"| ATG9
ATG["ATG"] -->|"phosphorylates"| ATG9
GFP["GFP"] -->|"interacts"| ATG9
LYSOSOME["LYSOSOME"] -->|"contributes to"| ATG9
AND["AND"] -->|"contributes to"| ATG9
APOPTOSIS["APOPTOSIS"] -->|"regulates"| ATG9
NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"] -->|"regulates"| ATG9| Target | Relation | Type | Str |
|---|---|---|---|
| autophagosome formation | activates | process | 0.70 |
| autophagosome biogenesis | regulates | process | 0.70 |
| Ms | regulates | disease | 0.65 |
| Als | regulates | disease | 0.65 |
| Tumor | regulates | disease | 0.65 |
| Bacterial Infection | interacts_with | disease | 0.65 |
| Als | interacts_with | disease | 0.65 |
| Infection | interacts_with | disease | 0.65 |
| AUTOPHAGY | interacts_with | gene | 0.60 |
| ATG12 | interacts_with | gene | 0.60 |
| ULK1 | interacts_with | gene | 0.60 |
| ATG5 | interacts_with | gene | 0.60 |
| Autophagy | interacts_with | pathway | 0.60 |
| BECLIN1 | interacts_with | gene | 0.60 |
| LC3 | interacts_with | gene | 0.60 |
| AUTOPHAGY | associated_with | gene | 0.60 |
| Autophagy | associated_with | pathway | 0.60 |
| Exocytosis | regulates | pathway | 0.60 |
| AUTOPHAGY | regulates | gene | 0.60 |
| Autophagy | regulates | pathway | 0.60 |
| Apoptosis | regulates | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ATG | phosphorylates | gene | 0.70 |
| ATG41 | interacts_with | protein | 0.70 |
| GFP | interacts_with | gene | 0.60 |
| ATG | interacts_with | gene | 0.60 |
| LYSOSOME | contributes_to | gene | 0.60 |
| APOPTOSIS | regulates | gene | 0.60 |
| NEURODEGENERATIVE DISEASES | regulates | gene | 0.60 |
| BCL-2 | regulates | gene | 0.60 |
| MICROTUBULES | contributes_to | gene | 0.60 |
| LYST | regulates | gene | 0.60 |
| ATG1 | associated_with | gene | 0.60 |
| ATG5 | associated_with | gene | 0.60 |
| CLN5 | associated_with | gene | 0.60 |
| CTSD | regulates | gene | 0.60 |
| MICROTUBULES | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ATG9 in their description or question text
No additional research found