protein 717 words KG: ATG9A
Contents

ATG9A Protein

🔬 Protein Info
Gene SymbolATG9A
AliasesATG9A protein
Chromosome2p24.1
Protein FamilyATG9 family
FunctionMembrane Source: Provides lipids for phagophore expansion
Subcellular LocalizationTrans-Golgi network, Endosomes, Plasma membrane, Autophagosomes
Molecular Weight139 kDa
Amino Acids790 aa
PathwaysAutophagy, Mitochondrial Function, Mitophagy, Nf-Κb, Stem Cell
UniProt IDQ7Z418
GeneCardsATG9A
Human Protein AtlasATG9A
Transmembrane DomainsMultiple transmembrane segments (typically 12-15)
N-terminal Cytoplasmic DomainContains sorting signals and ATG2 interaction motifs
C-terminal Cytoplasmic DomainRegulates protein localization and interactions
Associated DiseasesMs
InteractionsAND, ARAF, ATG, ATG101, ATG12, ATG13
KG Connections174 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Agent Input

Related Hypotheses (6)

APOE-Dependent Autophagy Restoration
Score: 0.88
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (8)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

Apoptosis in Neurodegeneration
entity · KG edge: protects_against
APEX2 Gene
gene · KG edge: regulates
ARAF Gene
gene · KG edge: activates
atg101
gene · KG edge: interacts_with
ATG12 — Autophagy Related 12
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

PARKIN regulates ATG9A
PINK1 regulates ATG9A
PTEN regulates ATG9A
RAB7A regulates ATG9A
ATG9A regulates TBK1
ATG9A regulates PTEN
ATG9A regulates PINK1
ATG9A regulates PARKIN
ATG9A regulates RAB7A
BCL2 regulates ATG9A

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