protein 683 words KG: VIMENTIN
Contents

Vimentin Protein

🔬 Protein Info
Gene SymbolVIMENTIN
Protein FamilyType III intermediate filament protein
Functionis a type III intermediate filament protein encoded by the VIM gene.
Primary Expressionmesenchymal cells, fibroblasts, and astrocytes in the central nervous system
Subcellular LocalizationCytoplasm, intermediate filaments
Molecular Weight57 kDa
Amino Acids466 aa
PathwaysAutophagy, NOTCH_SIGNALING, Notch Signal Sending, Notch Signaling, Proteasome
UniProt IDP08670
GeneCardsVIMENTIN
Human Protein AtlasVIMENTIN
Associated DiseasesGlioblastoma, Ms, Tumor
Known Drugs/Compoundscolumbianadin
InteractionsACTB, Actin, Akt, AKT, ALPHA-SYNUCLEIN, AND
KG Connections318 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (13)

Complement C1q Subtype Switching
Score: 0.66
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Positioning Dynamics Modulation
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62

Related Analyses (11)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived

See Also (10)

Apoptosis in Neurodegeneration
entity · KG edge: associated_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: biomarker_for
Astrocytes
entity · KG edge: inhibits
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: inhibits
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in

Knowledge Graph (12 edges)

VIMENTIN regulates NOTCH_SIGNALING
TUBULIN associated_with VIMENTIN
P62 associated_with VIMENTIN
MAP3K5 associated_with VIMENTIN
UBIQUITIN associated_with VIMENTIN
OCLN associated_with VIMENTIN
GJA1 regulates VIMENTIN
SQSTM1 associated_with VIMENTIN
CASP3 regulates VIMENTIN
GAPDH regulates VIMENTIN

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