| Gene Symbol | VIMENTIN |
| Chromosome | 10p13 |
| Protein Family | Type III intermediate filament protein |
| Function | is a type III intermediate filament protein encoded by the VIM gene. |
| Primary Expression | mesenchymal cells, fibroblasts, and astrocytes in the central nervous system |
| Subcellular Localization | Cytoplasm, intermediate filaments |
| Molecular Weight | 57 kDa |
| Amino Acids | 466 aa |
| Pathways | Autophagy, NOTCH_SIGNALING, Notch Signal Sending, Notch Signaling, Proteasome |
| UniProt ID | P08670 |
| GeneCards | VIMENTIN |
| Human Protein Atlas | VIMENTIN |
| Central α-helical rod domain | Responsible for dimerization and filament assembly PMID: 2847424 |
| N-terminal head domain | Regulates filament assembly and interaction with signaling molecules PMID: 21855637 |
| C-terminal tail domain | Mediates interactions with other cytoskeletal elements and organelles PMID: 8898344 |
| Associated Diseases | Glioblastoma, Ms, Tumor |
| Known Drugs/Compounds | columbianadin |
| Interactions | ACTB, Actin, Akt, AKT, ALPHA-SYNUCLEIN, AND |
| KG Connections | 318 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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