gene 3,026 words KG: GSK3B
Contents

GSK3B Gene - Glycogen Synthase Kinase 3 Beta

🧬 Gene Info
Gene SymbolGSK3B
AliasesGSK-3β, TPKII, Tau tubulin kinase (TTBK)
Chromosome3q13.33
Protein TypeSerine/Threonine Kinase
Functionis a constitutively active serine/threonine kinase encoded by the GSK3B gene that plays central and multifaceted roles in cellular physiology[@woodgett1990].
Molecular Weight47 kDa (420 amino acids)
Amino Acids420 aa
Exons12
PathwaysAkt, Cholesterol, Mapk, Microrna, Nf-Kb
GeneCardsGSK3B
Human Protein AtlasGSK3B
Associated DiseasesAging, ALS, Alzheimer, Alzheimer's disease, APOPTOSIS
Known Drugs/CompoundsANTHOCYANINS, Ficus deltoidea, LITHIUM, rapamycin, RAPAMYCIN, SB216763
InteractionsABCA1, ACETYL-COA, ACHE, Actin, AD, ADAM17
KG Connections1182 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Knowledge Graph (12 edges)

C3 regulates GSK3B
TCF4 associated_with GSK3B
MYC associated_with GSK3B
LC3 associated_with GSK3B
MTOR associated_with GSK3B
BECN1 associated_with GSK3B
CTNNB1 associated_with GSK3B
AXIN2 associated_with GSK3B
GAPDH associated_with GSK3B
SQSTM1 associated_with GSK3B

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