| Gene Symbol | STAT4 |
| Full Name | Signal Transducer and Activator of Transcription 4 |
| Chromosome | 2q32.2 |
| Protein Type | Transcription Factor |
| Function | is a critical transcription factor that mediates signaling by interleukin-12 (IL-12), interleukin-23 (IL-23), and type I interferons. |
| Primary Expression | immune cells and, at lower levels, in various tissues including brain |
| Amino Acids | 748 aa |
| Exons | 24 |
| Pathways | JAK-STAT signaling |
| UniProt ID | [Q14765](https://www.uniprot.org/uniprot/Q14765) |
| Ensembl ID | ENSG00000141510 |
| OMIM | 600556 |
| GeneCards | STAT4 |
| Human Protein Atlas | STAT4 |
| Associated Diseases | neurodegeneration |
| Interactions | ASC, COX2, FERROPTOSIS, GPX4, GSH, IFN |
| KG Connections | 65 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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