gene 697 words KG: SOX10
Contents

SOX10 Gene

🧬 Gene Info
Gene SymbolSOX10
Chromosome22q13.1
Protein TypeTranscription Factor
Functionis a critical transcription factor for neural crest development and glial cell differentiation.
Amino Acids446 aa
Exons3
UniProt IDP56937
NCBI Gene ID6663
Ensembl IDENSG00000100146
GeneCardsSOX10
Human Protein AtlasSOX10
Associated DiseasesAls, Tumor
InteractionsAGING, ALS, AND, CHAT, DNA, EGF
KG Connections51 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Oligodendrocyte White Matter Vulnerability
Score: 0.65
TREM2-mediated microglial tau clearance enhancement
Score: 0.59

Related Analyses (7)

Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · completed
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (15)

Myelin Basic Protein (MBP) - Biomarker
biomarker · KG edge: activates
Bipolar Cells in Visual Processing
cell · KG edge: expressed_in
Amyotrophic Lateral Sclerosis
redirect · KG edge: activates
Diseases Overview
disease · KG edge: associated_with
FUS (Redirect)
redirect · KG edge: activates

Knowledge Graph (12 edges)

SOX10 expressed_in DISC1
SOX10 expressed_in MBP
OVERVIEW associated_with SOX10
SOX10 associated_with NF1
SOX10 associated_with CDKN2A
SOX10 activates FUS
NESTIN activates SOX10
EGF activates SOX10
TUBULIN activates SOX10
SOX10 activates GDNF

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