| Gene Symbol | NF1 |
| Full Name | Neurofibromin 1 |
| Chromosome | 17q11.2 |
| Function | encodes a large tumor suppressor protein that negatively regulates the Ras signaling pathway. |
| Primary Expression | the nervous system: |
| Molecular Weight | 327 kDa |
| Amino Acids | 818 aa |
| Exons | 60 |
| Pathways | MAPK signaling |
| UniProt ID | [P21359](https://www.uniprot.org/uniprot/P21359) |
| Ensembl ID | ENSG00000196712 |
| OMIM | 613113 |
| GeneCards | NF1 |
| Human Protein Atlas | NF1 |
| Neuronal development | Regulation of neural progenitor proliferation and differentiation |
| Associated Diseases | Als, Cancer, epilepsy, frontotemporal dementia |
| Interactions | AKT, AKT3, AND, BRAF, CANCER, CDK4 |
| KG Connections | 253 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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