gene 1,081 words KG: RPS6
Contents

RPS6 Gene

🧬 Gene Info
Gene SymbolRPS6
AliasesRibosomal Protein S6
Chromosome9p21.1
Functionencodes a protein of 249 amino acids.
Primary Expressionneurons and glial cells
Molecular Weight28.7 kDa
Amino Acids249 aa
PathwaysmTOR signaling, mTOR pathway, mTOR
Ensembl IDENSG00000143977
GeneCardsRPS6
Human Protein AtlasRPS6
Associated DiseasesAD, ADH, AMI, Cancer, disease, Ischemia
Known Drugs/Compoundsrapamycin
InteractionsAKT, AKT1, APOE4, ATG, ATP, BECN1
KG Connections213 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (12)

CYP46A1 Overexpression Gene Therapy
Score: 0.95
Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.95
Transcriptional Autophagy-Lysosome Coupling
Score: 0.90
APOE-Dependent Autophagy Restoration
Score: 0.86
Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Nucleolar Stress Response Normalization
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

ATP P2X3 Receptor Neurons
cell · KG edge: regulates
Apoptosis in Neurodegeneration
entity · KG edge: associated_with
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
ACTB Gene
gene · KG edge: regulates
AKT1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

ACTB regulates RPS6
PPARA regulates RPS6
CAT regulates RPS6
SQSTM1 regulates RPS6
RPS6KB1 regulates RPS6
RAB7A regulates RPS6
SREBF1 regulates RPS6
EIF4EBP1 regulates RPS6
CTSD regulates RPS6
PPARGC1A regulates RPS6

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