| Gene Symbol | PSP |
| Full Name | Persephin |
| Chromosome | 19q13.33 |
| Protein Family | GDNF family |
| Function | Persephin mediates its effects through specific receptor interactions: |
| Pathways | Differentiation |
| GeneCards | PSP |
| Human Protein Atlas | PSP |
| Primary receptor | GFRα4 (GDNF Receptor Alpha 4) |
| Co-receptor | RET (Rearranged during transfection) |
| Motor Neuron Survival | Supports survival and differentiation of motor neurons |
| Dopaminergic Neuroprotection | Protects dopaminergic neurons in models of Parkinson's disease |
| Renal Development | Essential for ureteric bud development and kidney morphogenesis |
| Enteric Neurons | Supports survival of enteric nervous system neurons |
| Amyotrophic Lateral sclerosis (ALS) | Persephin has shown protective effects on motor neurons |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer's disease, dementia |
| Interactions | AGING, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND |
| KG Connections | 343 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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