gene 569 words KG: STX6
Contents

STX6 Gene

🧬 Gene Info
Gene SymbolSTX6
Protein TypeReceptor
FunctionSyntaxin 6 is a Q-SNARE protein localized primarily to the trans-Golgi network (TGN) and endosomes.
Subcellular Localizationprimarily to the *trans*-Golgi network (TGN) and endosomes
Ensembl IDENSG00000139334
GeneCardsSTX6
Human Protein AtlasSTX6
Associated DiseasesAls, Alzheimer, Alzheimer's disease, Ms, neurodegeneration
KG Connections42 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76

Related Analyses (5)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Astrocytes
cell · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
Progressive Supranuclear Palsy (PSP)
disease · KG edge: associated_with
Astrocytes
entity · KG edge: associated_with
DUSP10 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DUSP10 associated_with STX6
MAP1S associated_with STX6
PSP associated_with STX6
SP1 associated_with STX6
APOE associated_with STX6
TAU associated_with STX6
KIF13A associated_with STX6
TRIM24 associated_with STX6
STX6 associated_with MAPT
STX6 therapeutic_target Creutzfeldt-Jakob Disease

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