| Gene Symbol | PP2A |
| Full Name | Protein Phosphatase 2 Scaffold Subunit A Alpha |
| Aliases | PPP2R1A |
| Chromosome | 19q13.41 |
| Protein Type | Protein |
| Molecular Weight | 65 kDa |
| Pathways | Wnt, Notch pathway, mTOR, mtor, Wnt signaling |
| UniProt ID | P30153 |
| NCBI Gene ID | 5518 |
| Ensembl ID | ENSG00000114825 |
| OMIM | 605983 |
| GeneCards | PP2A |
| Human Protein Atlas | PP2A |
| Kinase/Phosphatase Balance | PP2A antagonizes numerous kinases including AKT, ERK, and GSK3β |
| Second Messenger Dephosphorylation | Regulates cAMP, Ca²⁺, and DAG signaling |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer's disease, disease, neurodegeneration |
| Known Drugs/Compounds | donepezil, Donepezil, DONEPEZIL, metformin, rapamycin, resveratrol |
| Interactions | AKT, AKT1, ALPHA-SYNUCLEIN, ALZHEIMER, ALZHEIMER'S DISEASE, AMBRA1 |
| KG Connections | 343 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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