Contents

PIK3CD Gene

🧬 Gene Info

Gene Symbol	PIK3CD
Aliases	PI3K catalytic subunit delta gene
Chromosome	1p36.22
Protein Type	Gene
Function	encodes a protein of 1,048 amino acids with a molecular weight of approximately 110 kDa.
Primary Expression	immune cells including T cells, B cells, natural killer cells, mast cells, and macrophages
Molecular Weight	110 kDa
Amino Acids	048 aa
Pathways	PI3K
GeneCards	PIK3CD
Human Protein Atlas	PIK3CD
p85-binding domain	Interacts with p85 regulatory subunits (PIK3R1, PIK3R2) that control enzyme activity and localization
C2 domain	Binds to cellular membranes through interactions with phospholipids
Helical domain	Involved in protein-protein interactions
Kinase domain	The catalytic center that phosphorylates PIP2 to generate PIP3
Associated Diseases	Alzheimer's disease, Parkinson's disease
Known Drugs/Compounds	dasatinib
Interactions	AKT, AKT1, AND, CANCER, GENES, INFLAMMATION
KG Connections	65 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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