gene 1,512 words KG: PIK3CB
Contents

PIK3CB — Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Beta

🧬 Gene Info
Gene SymbolPIK3CB
Full NamePhosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Beta
Chromosome22q13.33
Functionis a major signaling cascade in neurons
Amino Acids1048 aa
PathwaysPI3K, mTOR signaling
UniProt IDQ14184
NCBI Gene ID5293
Ensembl IDENSG00000077150
GeneCardsPIK3CB
Human Protein AtlasPIK3CB
Associated DiseasesAls, Ms
KG Connections73 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (3)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
APOE-Dependent Autophagy Restoration
Score: 0.85
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64

Related Analyses (2)

Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Experiment: Multi-Ethnic PD GWAS
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (15)

Cardiac MIBG Scan for Parkinsonism
diagnostic · KG edge: regulates
GBA (Redirect)
redirect · KG edge: expressed_in
mTOR Signaling Dysregulation in Progressive Supranuclea
event · KG edge: therapeutic_target
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
c9orf72-als-ftd-phenotype-mechanism
general · KG edge: expressed_in

Knowledge Graph (12 edges)

C9ORF72 expressed_in PIK3CB
CD8 associated_with PIK3CB
LRRK2 expressed_in PIK3CB
GBA expressed_in PIK3CB
WDFY3 expressed_in PIK3CB
PIK3CB expressed_in RALB
PIK3CB expressed_in GNAI3
PIK3CB expressed_in WIPI1
PIK3CA therapeutic_target PIK3CB
MTOR therapeutic_target PIK3CB

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)