gene 2,099 words KG: PENK
Contents

PENK Gene

🧬 Gene Info
Gene SymbolPENK
Full NameProenkephalin
Chromosome8p11.23
Protein FamilyOpioid precursor proteins
Functionis a 267-amino acid precursor protein with a molecular weight of approximately 29 kDa.
Molecular Weight29 kDa
Amino Acids267 aa
UniProt IDP01210
NCBI Gene ID5179
Ensembl IDENSG00000100644
OMIM131330
GeneCardsPENK
Human Protein AtlasPENK
Associated DiseasesMs, neurodegeneration
InteractionsCRH, EPILEPSY, PVALB, RGS5, SST
KG Connections54 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: expressed_in
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: associated_with
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: associated_with
Genes
index · KG edge: expressed_in
AKT1 Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

PENK expressed_in NCAM1
PENK expressed_in DNMT1
PENK expressed_in AKT1
PENK expressed_in COMT
PENK expressed_in DLGAP2
PENK expressed_in STAT3
PENK expressed_in ARG1
PENK expressed_in DRD2
PENK expressed_in DNMT3A
ICAM1 expressed_in PENK

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