Contents

DNMT3A Gene

🧬 Gene Info

Gene Symbol	DNMT3A
Full Name	DNA Methyltransferase 3 Alpha
Aliases	DNA Methyltransferase 3A
Chromosome	2p23
Protein Type	Transferase
Function	DNMT3A encodes DNA methyltransferase 3 alpha, a de novo DNA methyltransferase that establishes new DNA methylation patterns during development and in adult tissues.
Primary Expression	neurons during development and in adulthood
Molecular Weight	130 kDa
Pathways	Dna Methylation, Epigenetic
UniProt ID	[Q9Y6K4](https://www.uniprot.org/uniprot/Q9Y6K4)
Ensembl ID	ENSG00000119772
OMIM	602950
GeneCards	DNMT3A
Human Protein Atlas	DNMT3A
Associated Diseases	Als, Alzheimer, Cancer, Cardiovascular, Crohn'S Disease
Known Drugs/Compounds	GEMCITABINE
Interactions	AGING, ALZHEIMER, ALZHEIMER'S DISEASE, AND, ASXL1, BACE1
SciDEX Hypotheses	DNMT3A-Mediated de novo Methylation Corrects 'Epig
KG Connections	281 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING