| Gene Symbol | NDP52 |
| Chromosome | 21q22.12. |
| Protein Type | Gene |
| Function | Mitophagy: NDP52 recognizes ubiquitinated damaged mitochondria and recruits LC3-positive autophagosomes through its LIR domain |
| Primary Expression | various tissues with particularly high expression in immune cells and neurons |
| Amino Acids | 452 aa |
| Exons | 11 |
| Pathways | Adaptive Immunity, Autophagy, Complement, Immune Response, Innate Immunity |
| GeneCards | NDP52 |
| Human Protein Atlas | NDP52 |
| Associated Diseases | AD, ALI, Als, Alzheimer, AMI |
| Known Drugs/Compounds | dimethyl fumarate, EGCG, rapamycin |
| Interactions | ABCD3, ABP, ACAT1, ACTB, Actin, AIFM1 |
| KG Connections | 1120 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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