| Gene Symbol | SMCR8 |
| Full Name | SMCR8, SMOX Modifier 1 |
| Aliases | SMCR8 gene |
| Chromosome | 9p21.1 |
| Function | SMCR8 (SMCR8 - SMOX Modifier 1) is a protein coding gene that functions as a positive regulator of autophagy and lysosomal trafficking. |
| Primary Expression | neurons and glial cells, where it participates in cellular clearance mechanisms critical for neuronal health |
| Molecular Weight | 53 kDa |
| Amino Acids | 479 aa |
| Exons | 12 |
| Pathways | Autophagy, Mtor, Oxidative Stress |
| UniProt ID | Q8TBX5 |
| NCBI Gene ID | 94015 |
| GeneCards | SMCR8 |
| Human Protein Atlas | SMCR8 |
| Associated Diseases | AD, ALI, Als, AMI, amyotrophic lateral sclerosis, degenerative disease |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACTB, ALS, AMPK, amyotrophic lateral sclerosis, AMYOTROPHIC LATERAL SCLEROSIS, AND |
| KG Connections | 236 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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