gene 1,501 words KG: MYO7A
Contents

MYO7A — Myosin VIIa

🧬 Gene Info
Gene SymbolMYO7A
Full NameMyosin VIIa
Chromosome11q13.5
FunctionIt moves towards the plus (barbed) end of actin, which allows it to transport cargo from the cell body towards the periphery in epithelial cells and neurons 4.
Primary Expressionstereocilia of hair cells where it participates in the transport of proteins essential for stereocilia structure and function [6](https://pubmed
Molecular Weight221 kDa
Amino Acids215 aa
Exons49
PathwaysAutophagy, Invasion, Mitochondrial Function, Mitophagy, Toll-Like Receptor
UniProt ID[P12883](https://www.uniprot.org/uniprot/P12883)
Ensembl IDENSG00000135624
OMIM120650
GeneCardsMYO7A
Human Protein AtlasMYO7A
N-terminal motor domainContains the ATPase activity and actin-binding sites responsible for force generation
Associated DiseasesCancer, Lung Cancer, Tumor, USH1B
InteractionsADRA2B, AND, ASTROCYTE, ATF3, AUTOPHAGY, BECN1
KG Connections135 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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