| Gene Symbol | CHRM4 |
| Full Name | Cholinergic Receptor Muscarinic 4 |
| Chromosome | 11p12 |
| Function | encodes a 479-amino acid protein. |
| Primary Expression | the brain, where it plays crucial roles in modulating cognitive function, motor control, and neurotransmitter systems |
| Amino Acids | 479 aa |
| Pathways | Wnt |
| UniProt ID | [P48193](https://www.uniprot.org/uniprotkb/P48193/entry) |
| Ensembl ID | ENSG00000180720 |
| GeneCards | CHRM4 |
| Human Protein Atlas | CHRM4 |
| Striatum | Highest expression in the striatum, particularly in the indirect pathway medium spiny neurons |
| Cortex | Moderate expression in layer 5 pyramidal neurons |
| Hippocampus | Expression in CA1-CA3 regions and dentate gyrus |
| Thalamus | Significant expression in thalamic nuclei |
| Associated Diseases | neurodegeneration |
| Interactions | ASTROCYTE, Cytokine, CYTOKINES, GENES, IL13, MYO7A |
| KG Connections | 44 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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