gene 1,890 words KG: GRIA2
Contents

GRIA2 Gene

🧬 Gene Info
Gene SymbolGRIA2
Full NameGlutamate Ionotropic Receptor AMPA Type Subunit 2
Chromosome4q32.1
Functioncontrol and synaptic plasticity
Molecular Weight98 kDa
Amino Acids883 aa
PathwaysAutophagy, Mitophagy, autophagy pathway, mitophagy, ubiquitin-proteasome
UniProt IDP42263
NCBI Gene ID2892
Ensembl IDENSG00000120251
OMIM138247
GeneCardsGRIA2
Human Protein AtlasGRIA2
Associated DiseasesAls, Cancer, Tumor
InteractionsAND, ATF3, AUTOPHAGY, COX4I1, CYTOCHROME C, FOXO3
KG Connections106 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
APOE Isoform Conversion Therapy
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Stress-induced depression model sleep architecture analysis
validation · proposed · Score: 0.90

See Also (10)

glutamate
general · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
Genes
index · KG edge: associated_with
ATF3 Gene
gene · KG edge: activates
COX4I1
gene · KG edge: activates

Knowledge Graph (12 edges)

MYO7A activates GRIA2
MAP1LC3B activates GRIA2
OPTN activates GRIA2
PARKIN activates GRIA2
PINK1 activates GRIA2
XBP1 activates GRIA2
ATF3 activates GRIA2
TOMM20 activates GRIA2
PTEN activates GRIA2
USP30 activates GRIA2

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