| Gene Symbol | KMT2A |
| Full Name | MLL1 (Mixed-Lineage Leukemia 1) |
| Aliases | lysine methyltransferase 2A |
| Protein Family | SET1/MLL COMPASS Family |
| Protein Type | Transferase |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Nucleus |
| Molecular Weight | 432 kDa |
| Pathways | oxidative stress response |
| UniProt ID | Q16586 |
| GeneCards | KMT2A |
| Human Protein Atlas | KMT2A |
| Alzheimer's Disease | Altered expression and function contributes to epigenetic dysregulation of neuronal survival genes |
| Parkinson's Disease | May affect dopaminergic neuron survival through transcriptional mechanisms |
| Huntington's Disease | Involved in transcriptional dysregulation caused by mutant huntingtin protein |
| Associated Diseases | ALS |
| Interactions | ABCB1, ANK3, BCL-2, CACNA1G, CANCER, CRH |
| KG Connections | 65 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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